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Synicom (Dorzolamide & Timolol) Eye Drops, 5 ml - Barrett Hodgson Beard Apply it to your feetSynicom is a combination ophthalmic solution containing Dorzolamide (a carbonic anhydrase inhibitor) and Timolol (a beta blocker). It is used to lower elevated intraocular pressure (IOP) in patients with open angle glaucoma or ocular hypertension who require more than one medication. This fixed dose combination works through two complementary mechanisms: Dorzolamide reduces aqueous humor production, while Timolol increases its outflow. Using a single